Risky business of inhibitors: HLA haplotypes, gene polymorphisms, and immune responses
نویسندگان
چکیده
منابع مشابه
P-203: Investigating Association of HLA-G Gene Polymorphisms and Failed Implantation in Human Embryos
Background: HLA-G is a non-classical human leukocyte antigen expressed primarily in fetal tissues at the maternal-fetal interface. The unique structure of HLA-G molecule permits a restricted peptide presentation and allows the modulation of the immune system. There is now general agreement that HLA-G is an important immunotolerant molecule with the capability of inhibiting immune cell functions...
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15 صفحه اولPolymorphisms and haplotypes of the UDP-glucuronosyltransferase 2B7 gene promoter.
Identification of functional polymorphisms in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene predicting interpatient variability in the glucuronidation of drugs that are primarily metabolized by UGT2B7 has been the subject of many studies. These studies have shown linkage disequilibrium (LD) covering the region from -2 kb to 16 kb of the UGT2B7 gene. We identified three novel single-nucleoti...
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ژورنال
عنوان ژورنال: Hematology
سال: 2014
ISSN: 1520-4391,1520-4383
DOI: 10.1182/asheducation.v2014.1.372.3884771